Cryoneurolysis

Longer-lasting relief for nerve pain and spasticity

Cryoneurolysis is an emerging treatment for patients seeking longer-lasting relief from nerve pain and spasticity.

At GC Rehab, we offer cryoneurolysis as part of a comprehensive neurorehabilitation approach, combining procedural expertise with functional rehabilitation.

What is cryoneurolysis?

Cryoneurolysis uses controlled cold temperatures to temporarily disrupt nerve signalling.

This can:

Reduce pain
Decrease muscle overactivity
Improve movement and function

The nerve is not destroyed — it gradually regenerates over time, allowing for repeatable treatment.

Who this is for

Cryoneurolysis may be suitable for patients with:

Spasticity (e.g. stroke, brain injury, multiple sclerosis)
Post-stroke muscle overactivity
Peripheral nerve pain
Osteoarthritis-related pain (e.g. knee pain via genicular nerves)
Focal musculoskeletal pain syndromes

It is particularly useful when:

Symptoms persist despite therapy or medications
Botulinum toxin provides a limited or short-lived benefit
Function is restricted (e.g. walking, hygiene, limb positioning)

Common treatment targets

Depending on the condition, commonly treated nerves include:

Tibial nerve branches (spasticity affecting the calf)
Musculocutaneous nerve (upper limb spasticity)
Genicular nerves (knee osteoarthritis pain)
Peripheral sensory nerves for focal pain

What to expect

Performed in the clinic
Ultrasound-guided placement of a specialised probe
The procedure typically takes 60 to 90 minutes
Minimal downtime

Relief can last several months, depending on the nerve treated.

How this differs from other treatments

Cryoneurolysis targets the nerve directly.

Botulinum toxin acts at the muscle level
Medications provide systemic, often temporary relief
Surgery is more invasive and not always appropriate

Cryoneurolysis provides a targeted, reversible option with a longer duration than many non-surgical treatments.

When to consider referral

Referral may be appropriate for patients with:

Focal spasticity limiting function or care
Pain not responding to conservative treatment
Difficulty with gait, hygiene, or limb positioning
Recurrent symptoms despite standard therapies

Why GC Rehab

Specialist rehabilitation physician with experience in spasticity management and ultrasound-guided nerve procedures, including early clinical use of cryoneurolysis in Australia.